PHYTOSOMES AS AN INNOVATIVE DRUG DELIVERY STRATEGY

Phytosomes represent a groundbreaking advancement in herbal drug delivery systems, offering a novel approach to enhance the bioavailability and efficacy of phytoconstituents. Traditional herbal extracts often face challenges such as poor solubility, limited absorption, and rapid metabolism, which hinder their therapeutic potential. Phytosomes, formed by complexing phytoconstituents with phospholipids, particularly phosphatidylcholine, facilitate improved penetration of active compounds through biological membranes. This innovative delivery strategy not only increases the stability and absorption of plant-based bioactives but also ensures targeted delivery with reduced side effects. The current review discusses the structural characteristics, preparation techniques, and pharmacokinetic advantages of phytosomes, underscoring their potential to revolutionize herbal medicine formulations. Emphasizing recent research and clinical applications, this paper highlights phytosomes as a promising platform for enhancing the therapeutic efficacy and patient compliance of herbal drugs, paving the way for their broader acceptance in modern pharmacotherapy.